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1-Pentyl-3-(1-naphthoyl)indole (also called AM-678 and JWH-018) JWH-250 is a synthetic cannabinoid receptor agonist
that has been detected

Pharmacology
    JWH-018 is a full agonist of both the CB1 and CB2 cannabinoid receptors, with a reported binding affinity of 9.00 ±
5.00 nM at CB1 and 2.94 ± 2.65 nM at CB2 JWH-018 has an EC50 of 102 nM for human CB1 receptors, and 133 nM
for human CB2 receptors. JWH-018 produces bradycardia and hypothermia in rats at doses of 0.3-3 mg/kg, suggesting
potent cannabinoid-like activity.
JWH-250 is a synthetic cannabinoid receptor agonist that has been detected? The drug is a phenylacetylindole and it
works as an agonist at CB1 and CB2 receptors. It has an affinity of ~11 nM at CB1 and ~33 nM at CB2.  Those samples
contained 77-165 mg per product.
Because of the way it’s been sold, it’s likely people have encountered JWH-250 without realizing it. JWH-250 = 1-pentyl-
3-(2-methoxyphenylacetyl)indole. Unlike many of the older JWH series compounds, this compound does not have a
naphthalene ring,

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AM-678 is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors,
with some selectivity for CB2.

Combinations

Psychedelics - When used in combination with psychedelics, cannabinoids are capable of intensifying and extending the duration of both the visual and
cognitive effects with extreme efficiency. This should be used with caution if one is not experienced with psychedelics.
Dissociatives - When used in combination with dissociatives, the geometry, euphoria, dissociation and hallucinatory effects are often greatly enhanced.
Alcohol - When used in combination with alcohol, cannabinoids can cause feelings of extreme nausea, dizziness and changes in gravity. It is
recommended that one smoke before drinking and not the other way around unless they are extremely cautious.

List of the Cannabinoids not listed on the website but still avaialable in stock
JWH-007                                            JWH-253                                       JWH-350
JWH-015                                             JWH-213                                      JWH-336
JWH-019                                             JWH-205                                      JWH-300
JWH-030                                             JWH-181
JWH-047                                             JWH-166
JWH-048                                            JWH-139
JWH-258                                            JWH-387