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Domestic Returns

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Smoking crack allows it to reach the brain more quickly and thus brings an intense and immediate-but
very short-lived-high that lasts about fifteen minutes. And because addiction can develop even more
rapidly if the substance is smoked rather than snorted (taken in through the nose), an abuser can
become addicted after his or her first time trying crack.
PubChem CID: 656832
Chemical Names: Cocaine HCl; COCAINE HYDROCHLORIDE; UNII-XH8T8T6WZH; Cocaine hydrochloride.
Molecular Formula: C17H22ClNO4
IUPAC Name
methyl (1S,3S,4R,5R)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate;hydrochloride
Isomeric SMILES: CN1[[email protected]]2CC[[email protected]@H]1[[email protected]]([[email protected]](C2)OC(=O)C3=CC=CC=C3)C(=O)OC.C
InChI Key: PIQVDUKEQYOJNR-VZXSFKIWSA-N
Cocaine Hydrochloride. Cocaine binds to the dopamine, serotonin, and norepinephrine transport proteins and inhibits the re-uptake of dopamine, serotonin, and norepinephrine into pre-synaptic neurons. This leads to an accumulation of the respective neurotransmitters in the synaptic cleft and may result in increased postsynaptic receptor activation. Its effect on dopamine levels causes CNS stimulation and euphoria, and ultimately dependence. The mechanism of action through which cocaine exerts its local anesthetic effects is by binding to and blocking the voltage-gated sodium channels in the neuronal cell membrane. By stabilizing neuronal membranes, cocaine inhibits the initiation and conduction of nerve impulses and produces a reversible loss of sensation.
Uses
Cocaine is used by health care professionals to temporarily numb the lining of the mouth, nose, and throat (mucous membranes) before certain medical procedures (e.g., biopsy, stitches, wound cleaning). It is an anesthetic that works quickly to numb the area about 1-2 minutes after application. Cocaine also causes blood vessels to narrow, an effect that can decrease bleeding and swelling from the procedure.
a burst of energy
accelerated heart rate
dilated pupils
feelings of euphoria, exhilaration and confidence
hallucinations
increase in body temperature and blood pressure
loss of appetite
nausea and vomiting
nervousness
restlessness
the urge to have sex
tremors

How to use Cocaine HCL Solution,
This medication is applied directly to the inside of the mouth, nose, or throat by a health care professional, usually right before your procedure. It may be poured, sprayed, or applied with a cotton swab directly to the area. When using this medication in the nose, your health care professional may soak absorbent material with the solution, then insert it into the nose.
Problems Using Cocaine

People who use cocaine frequently can become addicted to it. The widespread abuse of cocaine has stimulated extensive
efforts to develop treatment programs for cocaine users. As with any drug addiction, this is a complex disease that involves
biological changes in the brain as well as myriad of social, familial, and other environmental problems. Therefore, treatment of
cocaine addiction must be comprehensive, and strategies need to assess the neurobiological, social, and medical aspects of the
patient’s drug abuse. Treatment options for cocaine dependence generally include:

Detoxification
Individual counselling
Group therapy
Presently, there are no FDA-approved medications to treat cocaine addiction. See your doctor for information and a referral, or
contact an alcohol and other drug service in your area if you think you’ve developed a problem with cocaine. You do not need to
suffer alone!
Cocaine is a powerfully addictive stimulant drug (Erythroxylum coca), Cocaine, also known as coke,
is a strong stimulant mostly used as a recreational drug. It is commonly snorted, inhaled as smoke, or
in a solutions injected into a vein. the powder is usually mixed with substances such as corn starch,
talcum powder and/or sugar or other drugs such as procaine (a local anesthetic) or amphetamines.
Cocaine is addictive due to its effect on the reward pathway in the brain. After a short period of use,
there is a high risk that dependence will occur. Its use also increases the risk of stroke, myocardial
infarction, lung problems in those who smoke it, blood infections, and sudden cardiac death.

1 gram costs $60 for good quality coke. 
1/8 (8 ball) costs $200 
1/4 costs $300 
1/2 ounce costs $1000 
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