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Generic Name: methylphenidate (oral)
Brand Names: Aptensio XR, Concerta, Cotempla XR-ODT, Metadate CD, Metadate ER, Methylin, QuilliChew ER, Quillivant
XR, Ritalin

What is methylphenidate?
Methylphenidate is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to
hyperactivity and impulse control.
Methylphenidate is used to treat attention deficit disorder (ADD), attention deficit hyperactivity disorder (ADHD), and
narcolepsy.
Methylphenidate may also be used for purposes not listed in this medication guide.

Uses
This medication is used to treat attention deficit hyperactivity disorder - ADHD. It works by changing the amounts of certain
natural substances in the brain. Methylphenidate belongs to a class of drugs known as stimulants. It can help increase your
ability to pay attention, stay focused on an activity, and control behavior problems. It may also help you to organize your tasks
and improve listening skills.

This medication is also used to treat a certain sleep disorder (narcolepsy).

Pharmacotherapeutic Uses
Previously stimulant drugs with DRI action have been used clinically include: amineptine, dexmethylphenidate,
difemetorex,fencamfamine, medifoxamine, nomifensine, prolintane, and pyrovalerone.

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Methylphenidate may be used in addition to an antidepressant for refractory major depressive disorder. It can also improve
depression in several groups including stroke, cancer, and HIV-positive patients. However, the use of stimulants such as
methylphenidate in cases of treatment-resistant depression is controversial. Stimulants may have fewer side-effects than
tricyclic antidepressants in the elderly and medically ill. In individuals with terminal cancer, methylphenidate can be used to
counteract opioid-induced somnolence, to increase the analgesic effects of opioids, to treat depression, and to improve
cognitive function.

Methylphenidate and other stimulants are also used to improve vasoconstriction in the treatment of orthostatic intolerance (OI),
a dysautonomic/autonomic nervous system (ANS) disorder.
We also have 4-Fluoromethylphenidate - Research Chemical
4-Fluoromethylphenidate (4F-MPH) is a stimulant drug that acts as a higher efficiency dopamine reuptake inhibitor than its
close analogue methylphenidate. It was initially developed as a replacement for ethylphenidate. Anecdotal reports suggest
that 4F-MPH is considerably more potent with fewer side effects.